KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKAA2
All Species:
32.73
Human Site:
T221
Identified Species:
60
UniProt:
P54646
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54646
NP_006243.2
552
62320
T221
F
D
D
E
H
V
P
T
L
F
K
K
I
R
G
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001086410
550
62775
T223
F
D
D
D
H
V
P
T
L
F
K
K
I
C
D
Dog
Lupus familis
XP_546691
722
81319
T391
F
D
D
E
H
V
P
T
L
F
K
K
I
R
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8BRK8
552
61988
T221
F
D
D
E
H
V
P
T
L
F
K
K
I
R
G
Rat
Rattus norvegicus
Q09137
552
62239
T221
F
D
D
E
H
V
P
T
L
F
K
K
I
R
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506315
519
59478
T192
F
D
D
D
H
V
P
T
L
F
K
K
I
C
D
Chicken
Gallus gallus
Q9IA88
798
88848
T230
F
D
G
P
N
L
P
T
L
R
Q
R
V
L
E
Frog
Xenopus laevis
NP_001088426
560
64038
T232
F
D
D
D
H
V
P
T
L
F
K
K
I
C
D
Zebra Danio
Brachydanio rerio
Q6NSM8
1187
130949
N263
F
D
G
S
T
L
Q
N
L
R
A
R
V
L
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623371
515
58559
G195
I
S
G
K
L
Y
A
G
P
E
V
D
I
W
S
Nematode Worm
Caenorhab. elegans
Q95ZQ4
626
70425
S292
F
D
D
E
H
V
P
S
L
F
R
K
I
K
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38997
535
61163
G218
I
S
G
K
L
Y
A
G
P
E
V
D
V
W
S
Baker's Yeast
Sacchar. cerevisiae
P06782
633
72027
V259
F
D
D
E
S
I
P
V
L
F
K
N
I
S
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
76.4
73.8
N.A.
97.6
98.1
N.A.
71.1
27.3
75.3
22.3
N.A.
N.A.
66.1
53.6
N.A.
Protein Similarity:
100
N.A.
86.7
75.2
N.A.
98.5
99
N.A.
81.1
42.6
85
32.6
N.A.
N.A.
77.7
65.6
N.A.
P-Site Identity:
100
N.A.
80
100
N.A.
100
100
N.A.
80
33.3
80
20
N.A.
N.A.
6.6
73.3
N.A.
P-Site Similarity:
100
N.A.
86.6
100
N.A.
100
100
N.A.
86.6
66.6
86.6
40
N.A.
N.A.
13.3
93.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
44.9
33.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
62.3
50.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
60
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
16
0
0
0
8
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
24
0
% C
% Asp:
0
85
70
24
0
0
0
0
0
0
0
16
0
0
24
% D
% Glu:
0
0
0
47
0
0
0
0
0
16
0
0
0
0
8
% E
% Phe:
85
0
0
0
0
0
0
0
0
70
0
0
0
0
0
% F
% Gly:
0
0
31
0
0
0
0
16
0
0
0
0
0
0
31
% G
% His:
0
0
0
0
62
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
16
0
0
0
0
8
0
0
0
0
0
0
77
0
0
% I
% Lys:
0
0
0
16
0
0
0
0
0
0
62
62
0
8
0
% K
% Leu:
0
0
0
0
16
16
0
0
85
0
0
0
0
16
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
8
0
0
8
0
0
0
8
0
0
8
% N
% Pro:
0
0
0
8
0
0
77
0
16
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
8
0
0
0
8
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
16
8
16
0
31
0
% R
% Ser:
0
16
0
8
8
0
0
8
0
0
0
0
0
8
31
% S
% Thr:
0
0
0
0
8
0
0
62
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
62
0
8
0
0
16
0
24
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
16
0
% W
% Tyr:
0
0
0
0
0
16
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _